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发表文章
1.  Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe.
Shrimp, J.H.; Hu, J.; Dong, M.; Wang, B.S.; MacDonald, R.;Jiang, H.;Hao, Q.; Yen, A.; Lin, H.
J. Am. Chem. Soc., 2014, 136, 5656-5663.

 

2.  SIRT6 Regulates TNF-alpha Secretion through Hydrolysis of Long-Chain Fatty Acyl Lysine.
Jiang, H. ¶; Khan, S. ¶; Wang, Y. ¶; Charron, G.; He, B.; Sebastian, C.; Du, J.; Kim, R.; Ge, E.;Mostoslavsky, R.; Hang, H. C.; Hao, Q.; Lin, H.
Nature, 2013, 496, 110-113. (¶ Authors contributed equally.)

 

3.  Identification of ADP-ribosylation Sites of CD38 Mutants by Precursor Ion Scanning Mass Spectrometry.
Jiang, H.; Sherwood, R.; Zhang, S.; Zhu, X.; Liu, Q.; Graeff, R.; Kriksunov, I. A.; Lee, H. C.; Hao, Q.; Lin, H.
Anal.Biochem., 2013, 433, 218-226.

 

4.   Chemogenomic Approach Identified Yeast YLR143W as DiphthamideSynthetase.
Su, X.; Lin, Z.; Chen, W.; Jiang, H.; Zhang, S.; Lin, H.
Proc. Natl. Acad. Sci. U S A., 2012, 109, 19983-19987.

 

5.  Labeling Substrate Proteins of Poly(ADP-ribose) Polymerases with Clickable NAD Analogue
Jiang, H.; Lin, H.
Current Protocols in Chemical Biology, 2012, 4, 19-34.

 

6.  YBR246W is Required for the Third Step of Diphthamide Biosynthesis.
Su, X.; Chen, W.; Lee, W.; Jiang, H.; Zhang, S.; Lin, H.
J. Am. Chem. Soc., 2012, 134, 773-776.

 

7.  Sirt5 is an NAD-dependent Protein Lysine Demalonylase and Desuccinylase.
Du, J.; Zhou, Y.; Su, X.; Yu, J. J.; Khan, S.; Jiang, H.; Kim, J.; Woo, J.; Kim, J.-H.; Choi, B. H.; He, B.; Zhang, S.; Cerione, R. A.; Auwerx, J.; Hao, Q.; Lin, H.
Science, 2011, 334, 806-809.

 

8.  ATRA-induced HL-60 Myeloid Leukemia Cell Differentiation Depends on the CD38 Cytosolic Tail Needed for Membrane Localization, but CD38 Enzymatic Activity is Unnecessary.
Congleton, J.; Jiang, H.; Malavasi, F.; Lin, H.; Yen, A.
Exp. Cell Res., 2011, 317, 910-919.

 

9.  Clickable NAD Analogues for Labeling Substrate Proteins of Poly(ADP-ribose) Polymerases.
Jiang, H.; Kim, J. H.; Frizzell, K.; Kraus, W. L.; Lin, H.
J. Am. Chem. Soc., 2010, 132, 9363-9372.

 

10. Structural Basis for Enzymatic Evolution from a Dedicated ADP-ribosyl Cyclase to a Multi-functional NAD Hydrolase.
Liu, Q.; Graeff, R.; Kriksunov, I. A.; Jiang, H.; Zhang, B.; Oppenheimer, N.; Lin, H.; Potter, B. V. L.; Lee, H. C.; Hao, Q.
J. Biol. Chem., 2009, 284, 27637-27645.

 

11. The Partial Substrate Dethiaacetyl -Coenzyme A Mimics All Critical Carbon Acid Reactions in the Condensation Half-Reaction Catalyzed by Thermoplasmaacidophilum Citrate Synthase.
Kurz, L. C.; Constantine, C. Z.; Jiang, H.; Kappock, T. J.
Biochemistry, 2009, 48, 7878-7891.

 

12. Mechanism-Based Small Molecule Probes for Labeling CD38 on Live Cells.
Jiang, H.; Congleton, J.; Liu, Q.; Merchant, P.; Malavasi, F.; Lee, H. C. ; Hao, Q.; Yen, A.; Lin, H.
J. Am. Chem. Soc., 2009, 131, 1658-1659.

 

13. Investigating the ADP-ribosyltransferase Activity of Sirtuins with NAD Analogs and 32P-NAD.
Du, J.; Jiang, H.; Lin, H.
Biochemistry, 2009, 48, 2878–2890.

 

14. A Study on the Reactions of NADH Models with Electron-Deficient Alkenes. A Probe for the Extreme of Concerted Electron-Hydrogen Atom Transfer Mechanism.
Fang, X.-Q.; Xu, H.-J.; Jiang, H.; Liu, Y.-C.; Fu, Y.; Wu, Y.-D.
Tetrahedron Lett., 2009, 50, 312-315.

 

15. Covalent and Non-CovalentIntermediates of an NAD Utilizing Enzyme - Human CD38.
Liu, Q.; Kriksunov, I.A.; Jiang, H.; Graeff, R.; Lin, H.; Lee, H.C.; Hao, Q.
Chem. Biol., 2008, 15,1068-1078.

 

16. Multiple Active Site Histidine Protonation States in Acetobacteraceti N5-Carboxyaminoimidazole Ribonucleotide Mutase Detected by REDOR NMR.
Schaefer, J.; Jiang, H.; Ransome, A. E.; Kappock, T. J.
Biochemistry, 2007, 46, 9507-9512.

 

17. Structure of a NADH-Insensitive Hexameric Citrate Synthase that Resists Acid Inactivation.
Francois, J. A.; Starks, C. M., Sivanuntakorn, S.; Jiang, H.; Ransome, A. E.; Nam, J.-W.; Constantine, C. Z.; Kappock, T. J.
Biochemistry, 2006, 45, 13487-13499.

 

18. Photo-induced Coupling Reaction of 1,1-Diphenyl-2,2-dicyano-ethylene with 10-Methyl-9,10-dihydroacridine.
Jiang, H.; Liu, Y.-C.; Wang, G.-W.; Wu, Y.-D.; Wang, Q.-M.; Mak, T. C. W.
Chinese Chem. Lett., 2004, 15, 159-162.

 

19. Novel Photo-induced Coupling Reactions of 9-Fluorenylidenemalononitrile or 1,1-Diphenyl-2,2-dicyanoethylene with 10-Methyl-9,10-dihydroacridine. A Study on the Photophysics of the Reaction.
Jiang, H.; Liu, Y.-C.; Wang, G.-W.; Wu, L.-Z.; Tong, Z.-H.
Chinese J. Chem., 2003, 21, 1400-1402.

 

20. Novel Photo-induced Coupling Reaction of 9-Fluorenylidenemalononitrile with 10-Methyl-9,10-dihydroacridine.
Jiang, H.; Liu, Y.-C.; Li J.; Wang, G.-W.; Wu, Y.-D.; Wang, Q.-M.; Mak, T. C. W.
Chem. Commun., 2002, 882-883.

 

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